Senior Director of DMPK/ADME (Biotechnology, Boston or Copenhagen)

Job summary

This role involves leading the Drug Metabolism and Pharmacokinetics (DMPK) capabilities across various modalities, focusing on strategic leadership and operational delivery of nonclinical DMPK activities. The position emphasizes building and scaling DMPK capabilities, particularly at the Boston site, while ensuring integration with Copenhagen operations.

Qualifications

• PhD in pharmaceutical sciences or a related field with substantial industry experience.
• Extensive knowledge of DMPK challenges across multiple modalities.
• Proven leadership experience in developing high-performing scientific teams.
• Experience with regulatory DMPK content and IND/CTA support.
• Ability to balance scientific rigor with project priorities and resource constraints.

Responsibilities

• Lead DMPK/ADME strategy and execution across the portfolio.
• Build and mentor DMPK capabilities at the Boston site, ensuring alignment with Copenhagen standards.
• Oversee bioanalytical method development and nonclinical assay validation.
• Manage in vitro ADME activities and in vivo pharmacokinetics.
• Deliver high-quality nonclinical PK summaries and integrated DMPK data packages.
• Implement automation and AI-enabled approaches within DMPK workflows.
• Collaborate with cross-functional teams and oversee external partners and CROs.

Skills

• Strong communication skills for translating complex DMPK data.
• Ability to operate in a fast-paced, multi-modal pipeline environment.
• Experience with lab automation and AI-enabled workflows is a plus.

Education

• PhD in pharmaceutical sciences or a similar field.

Tools

• Familiarity with DMPK software and bioanalytical tools is advantageous.