Postdoctoral Researcher in Metabolic Engineering

Job summary

This position focuses on advancing microbial cell factories for isoprenoid biosynthesis using CO₂-derived feedstocks. The role involves interdisciplinary collaboration to develop scalable bioprocesses aimed at establishing sustainable chemical production routes.

Qualifications

• PhD in metabolic engineering, biotechnology, or a related field.
• Experience in microbial physiology and metabolic engineering of non-model bacteria, including CRISPR/Cas methods.
• Hands-on experience with analytics (e.g., GC-MS, LC-MS) and bioreactor cultivation.
• Familiarity with metabolic design principles and systems-level metabolic engineering approaches.
• Strong collaborative mindset and excellent communication skills in English.

Responsibilities

• Design and optimize microbial strains for isoprenoid biosynthesis using MEP and MVA pathways.
• Develop high-throughput screening methods for quantifying isoprenoid flux.
• Implement optimized biosynthetic pathways in microbial cell factories for P2X feedstock assimilation.
• Lead strain engineering efforts using CRISPR/Cas systems.
• Conduct bioreactor experiments to assess strain performance and scalability.
• Collaborate with various project teams and disseminate findings through publications and presentations.

Education

• A PhD degree (or equivalent) is required.

Tools

• CRISPR/Cas systems, GC-MS, LC-MS, bioreactors.